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Z-Thr-Gly-OEt, also known as Z-β-Alanine-Glycine-Ethyl Ester, is a tripeptide derivative featuring a β-alanine residue, a glycine residue, and an ethyl ester group. The "Z" prefix stands for the benzyloxycarbonyl (Cbz) protecting group, which is commonly used in peptide synthesis to prevent unwanted side reactions. Z-Thr-Gly-OEt is a valuable intermediate in the synthesis of various peptides and pharmaceuticals, as it can be further modified or elongated to create more complex structures. The ethyl ester group enhances the solubility of the compound in organic solvents, facilitating its use in chemical reactions. Z-Thr-Gly-OEt is also relevant in the study of peptide chemistry and drug design, as it can be incorporated into larger molecules to investigate their biological activities and potential therapeutic applications.

17451-78-4

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17451-78-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 17451-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,5 and 1 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17451-78:
(7*1)+(6*7)+(5*4)+(4*5)+(3*1)+(2*7)+(1*8)=114
114 % 10 = 4
So 17451-78-4 is a valid CAS Registry Number.

17451-78-4Downstream Products

17451-78-4Relevant academic research and scientific papers

Synthesis and Characterisation of some New Diazopeptides

Challis, Brian C.,Latif, Farida

, p. 1005 - 1009 (2007/10/02)

The synthesis of eight new diazopeptides by aprotic diazotisation with N2O4 is described for glycylglycine, triglycine, pentaglycine, L-leucylglycine and the ethyl esters of L-leucylglycine, L-alanylglycine, L-serylglycine and L-threonylglycine.The diazo derivatives (7) - (10) of the parent peptides are isolated as calcium salts.The UV-vis., IR, 1H NMR and MS properties of the new diazopeptides are reported together with those for the diazo derivative of glycylglycine ethyl ester and glycylglycinamide.

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