17452-12-9 Usage
General Description
1-(4-Chlorophenyl)imidazoline-2-thione, also known as tiabendazole, is a chemical compound with antifungal properties. It is commonly used as a fungicide to control a wide range of fungal infections in plants and fruits. Tiabendazole works by inhibiting the growth of fungi and preventing the spread of infections in crops, making it an important tool in agriculture and food preservation. Additionally, it has shown potential as a pharmaceutical agent for the treatment of certain parasitic infections in humans and animals. However, tiabendazole is known to have low acute toxicity in mammals and is classified as a possible human carcinogen, so it should be handled and used with caution.
Check Digit Verification of cas no
The CAS Registry Mumber 17452-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,5 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17452-12:
(7*1)+(6*7)+(5*4)+(4*5)+(3*2)+(2*1)+(1*2)=99
99 % 10 = 9
So 17452-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2S/c10-7-1-3-8(4-2-7)12-6-5-11-9(12)13/h1-6H,(H,11,13)
17452-12-9Relevant articles and documents
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors
Zhan, Peng,Liu, Xinyong,Zhu, Junjie,Fang, Zengjun,Li, Zhenyu,Pannecouque, Christophe,Clercq, Erik De
experimental part, p. 5775 - 5781 (2009/12/28)
A series of 2-(1-aryl-1H-imidazol-2-ylthio)acetamide [imidazole thioacetanilide (ITA)] derivatives were synthesized and evaluated as potent inhibitors of human immunodeficiency virus type-1 (HIV-1). Among them, the most potent HIV-1 inhibitors were 4a5 (E