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1-(4-Chlorophenyl)imidazoline-2-thione, commonly known as tiabendazole, is a chemical compound characterized by its antifungal properties. It is a versatile substance that has found applications in both agricultural and pharmaceutical contexts due to its ability to inhibit fungal growth and treat parasitic infections.

17452-12-9

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17452-12-9 Usage

Uses

Used in Agricultural Industry:
1-(4-Chlorophenyl)imidazoline-2-thione is used as a fungicide for controlling a broad spectrum of fungal infections in plants and fruits. It serves to prevent the spread of infections in crops, thereby playing a crucial role in agriculture and food preservation.
Used in Pharmaceutical Industry:
1-(4-Chlorophenyl)imidazoline-2-thione is used as a pharmaceutical agent for the treatment of certain parasitic infections in humans and animals. Its antifungal properties make it a potential candidate for therapeutic use in combating parasitic diseases.
However, it is important to note that tiabendazole is known to have low acute toxicity in mammals and is classified as a possible human carcinogen. Therefore, it should be handled and used with caution to ensure safety and minimize potential health risks.

Check Digit Verification of cas no

The CAS Registry Mumber 17452-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,5 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 17452-12:
(7*1)+(6*7)+(5*4)+(4*5)+(3*2)+(2*1)+(1*2)=99
99 % 10 = 9
So 17452-12-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H7ClN2S/c10-7-1-3-8(4-2-7)12-6-5-11-9(12)13/h1-6H,(H,11,13)

17452-12-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-Chlorophenyl)-1H-imidazole-2-thiol

1.2 Other means of identification

Product number -
Other names 1-(4-Chlorophenyl)imidazoline-2-thione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17452-12-9 SDS

17452-12-9Relevant academic research and scientific papers

Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

Zhan, Peng,Liu, Xinyong,Zhu, Junjie,Fang, Zengjun,Li, Zhenyu,Pannecouque, Christophe,Clercq, Erik De

experimental part, p. 5775 - 5781 (2009/12/28)

A series of 2-(1-aryl-1H-imidazol-2-ylthio)acetamide [imidazole thioacetanilide (ITA)] derivatives were synthesized and evaluated as potent inhibitors of human immunodeficiency virus type-1 (HIV-1). Among them, the most potent HIV-1 inhibitors were 4a5 (E

Structure activity relationships in reactivators of organophosphorus inhibited acetylcholinesterase. VII. 1 Aryl 2 hydroxyiminomethyl 3 methylimidazolium iodides

Franchetti,Grifantini,Martelli,Stein

, p. 18 - 22,21,22 (2007/10/05)

A series of 1 aryl 2 hydroxyiminomethyl 3 methylimidazolium iodides, where the aryl group is either phenyl or substituted phenyl, was prepared and tested for their reactivating potency on phosphorylated acetylcholinesterase (AChE) and for anti AChE activity. The in vitro testing revealed that some of the new compounds are good reactivators. Correlations between their structure and biological activities have been attempted.

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