17453-27-9Relevant academic research and scientific papers
Palladium-catalyzed one-pot synthesis of diazoles via tert-butyl isocyanide insertion
Fan, Xiang-Yuan,Jiang, Xiao,Zhang, Ying,Chen, Zhen-Bang,Zhu, Yong-Ming
, p. 10402 - 10408 (2015)
An efficient one-pot palladium-catalyzed reaction for the synthesis of diazoles from readily available hydrazides and aryl halide via isocyanide insertion/cyclization sequence has been developed. This methodology efficiently constructs diazoles in good to excellent yields with the advantages of wide functional group tolerance and operational simplicity.
