174591-36-7

Basic information

• Product Name: (3R,6S,1'S)-3,6-dimethyl-4-N-(1'-phenethyl)-1,4-morpholin-2,5-dione
• Synonyms: (3R,6S,1'S)-3,6-dimethyl-4-N-(1'-phenethyl)-1,4-morpholin-2,5-dione
• CAS NO: 174591-36-7
• Molecular Weight: 247.294
• Mol File: 174591-36-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,6S,1'S)-3,6-dimethyl-4-N-(1'-phenethyl)-1,4-morpholin-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,6S,1'S)-3,6-dimethyl-4-N-(1'-phenethyl)-1,4-morpholin-2,5-dione(174591-36-7)
• EPA Substance Registry System: (3R,6S,1'S)-3,6-dimethyl-4-N-(1'-phenethyl)-1,4-morpholin-2,5-dione(174591-36-7)

Safety Data

• Hazardous Substances Data: 174591-36-7(Hazardous Substances Data)

Upstream product

• 84049-31-0 (2R,4S)-3-aza-2-methyl-4-phenyl-ethylpentanoate 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 174591-35-6 (6S,1'S)-6-methyl-4-(1'-phenylethyl)-1,4-morpholine-2,5-dione 
• 74-88-4 methyl iodide 
• 217952-09-5 (R)-2-[((S)-2-Acetoxy-propionyl)-((S)-1-phenyl-ethyl)-amino]-propionic acid ethyl ester 

Downstream Products

• 338-69-2 D-Alanine 

Relevant articles and documents

Stereoselective synthesis of uncommon α,α'-dialkyl-α- aminoacids. Part 1

The alkylation of the diastereomeric mixture of chiral morpholinone derivatives 4 and 5 occurs with good yield and trans induction. Cleavage of the alkylated products 6a,b,c,e gives enantiomerically pure uncommon (and sterically constrained) α,α'-dialkyl-α-aminoacids. The absolute configuration of the new stereocentres of 4, 5, 6 and 7 has been assigned on the basis of the 1H-NMR spectra and NOE measurements.