17461-01-7Relevant academic research and scientific papers
Diastereoselective specificity for the hydrolysis of dipeptide esters in aqueous media
Ueoka, Ryuichi,Goto, Kouichi,Tanoue, Osamu,Miki, Atsushi,Yoshimitsu, Shinya,Imamura, Chikara,Ihara, Yasuji,Murakami, Yukito
, p. 73 - 74 (2007/10/03)
The diastereoselectivity for the hydrolysis of p-methoxycarbonylphenyl N-(benzyloxycarbonyl)-D(L)-phenylalanyl-L-leucinate in aqueous solution was inverted by changing concentrations of the substrates or the reaction temperature. The monomer-aggregate transition operated on the LL-substrate, which was suggested by the spectroscopic measurements, seems to be responsible for such behavior.
