174611-14-4Relevant articles and documents
Inhibition of matrix metalloproteinases: An examination of the S1' pocket
Miller, Andrew,Askew, Marion,Beckett, R. Paul,Bellamy, Claire L.,Bone, Elisabeth A.,Coates, Rachael E.,Davidson, Alan H.,Drummond, Alan H.,Huxley, Philip,Martin, Fionna M.,Saroglou, Lydia,Thompson, Alison J.,Van Dijk, Sonja E.,Whittaker, Mark
, p. 193 - 198 (2007/10/03)
Peptidomimetic carboxylate- and hydroxamate-based inhibitors of matrix metalloproteinases containing extended P1' groups have been prepared. Potent inhibition and good selectivity for MMP-2 has been observed for the compounds produced.