174648-20-5

Upstream product

• 6393-40-4 4-Amino 3-nitro-benzonitrile 
• 17626-40-3 4-cyano-1,2-phenylenediamine 
• 104-87-0 4-methyl-benzaldehyde 

Downstream Products

• 174648-33-0 2'-p-tolyl-5-cyano-2,5'-bi-1H-benzimidazole 
• 23554-98-5 2'-(4-hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole 
• 174648-27-2 2-p-tolyl-5-formylbenzimidazole 

Relevant academic research and scientific papers

Substituted 2,5'-bi-1H-benzimidazoles: Topoisomerase I inhibition and cytotoxicity

Several 2'-aryl-5-substituted-2,5'-bi-1H-benzimidazole derivatives were synthesized and evaluated as topoisomerase I poisons and for their cytotoxicity toward the human lymphoblast cell line RPMI 8402. This study focused on 18 2,5'-bi-1H-benzimidazole der

Substituted 2-Phenyl-benzimidazoles and their use as pharmaceuticals

The present invention relates to derivatives of 2-phenyl-benzimidazoles of the general formula (I), in which X, R, R1 to R3 and n have the meanings indicated in the claims, which modulate the transcription of endothelial nitric oxide (NO) synthase and are