17465-98-4

Usage

Uses

Used in Pharmaceutical Research:
6-CHLORO-N4-(4-METHOXYPHENYL)-4,5-PYRIMIDINEDIAMINE is used as a research compound for the development of new antineoplastic agents, given its potential to contribute to cancer treatment.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-CHLORO-N4-(4-METHOXYPHENYL)-4,5-PYRIMIDINEDIAMINE is utilized as a chemical entity for exploring its biological and chemical properties, which may lead to the discovery of its pharmacological potential.
Used in Antineoplastic Drug Development:
6-CHLORO-N4-(4-METHOXYPHENYL)-4,5-PYRIMIDINEDIAMINE is employed as a key component in the formulation of antineoplastic drugs, targeting the inhibition of cancer cell growth and proliferation.
Used in Cancer Treatment:
In the medical industry, 6-CHLORO-N4-(4-METHOXYPHENYL)-4,5-PYRIMIDINEDIAMINE is used as a potential therapeutic agent for cancer treatment, due to its antineoplastic properties that may help in managing and combating various types of cancer.

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 104-94-9 4-methoxy-aniline 

Downstream Products

• 17466-05-6 7-chloro-3-(4-methoxy-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine 
• 84905-69-1 N-(4-methoxyphenyl)-5H-pyrrolo[3,2-d]pyrimidin-4-amine 
• 21313-95-1 6-chloro-9-(4-methoxyphenyl)-9H-purine 

Relevant academic research and scientific papers

A One-Pot Synthesis of Highly Functionalized Purines

Highly substituted purines were synthesized in good to high yields through a one-pot straightforward metal-free scalable method, using the Traube synthesis adapted to Vilsmeier-type reagents. From 5-amino-4-chloropyrimidines, new 9-aryl-substituted chloropurines and intermediates for peptide nucleic acid synthesis were prepared. Variant procedures allowing a rapid synthesis of ribonucleosides and 7-benzylpurine from 5-amidino-6-aminopyrimidines are also reported to illustrate the high potential of this versatile toolbox. This route appears to be particularly interesting in the field of nucleic acids for a direct and rapid access to various new 8-alkylpurine nucleosides.

An efficient synthesis of 4,6-substituted pyrrolo[3,2-d]pyrimidines by silver-catalyzed cyclization of acetylene amine

A silver catalyzed cyclization of acetylene amine was developed to synthesize 4,6-substituted pyrrolo[3,2-d]pyrimidine, a bioactive isosteric scaffold of purine. Starting from simple commercially available acetylenes and pyrimidines, the method was found

Catalytic action of azolium salts. IX. Synthesis of 6-aroyl-9H-purines and their analogues by nucleophilic aroylation catalyzed by imidazolium or benzimidazolium salt

In the presence of 1,3-dimethylimidazolium iodide (1), 6-chloro-9- phenyl-9H-purine (7) and 4-chloro-5,6-dimethylpyrrolo[2,3-d]pyrimidines 40- 42 underwent nucleophilic aroylation with arenecarbaldehydes (5) to give the corresponding fused aroylpyrimidine