174728-03-1 Usage
Uses
2-Chloro-4-piperazin-1-yl-pyrimidine is used as a reactant in the preparation of piperazinylpyrazines and analogs as serotonin 5HT2C receptor modulators for treatment of CNS disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 174728-03-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,7,2 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 174728-03:
(8*1)+(7*7)+(6*4)+(5*7)+(4*2)+(3*8)+(2*0)+(1*3)=151
151 % 10 = 1
So 174728-03-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H11ClN4/c9-8-11-2-1-7(12-8)13-5-3-10-4-6-13/h1-2,10H,3-6H2
174728-03-1Relevant articles and documents
Study on chemical modification and analgesic activity of N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl) piperazine-1-carboxamide
Gao, Mengkang,Hu, Jing,Li, Qifei,Nie, Cunbin,Qian, Hai,Qiao, Yue,Qiao, Zhenrui,Wang, Qiang,Wang, Yusui,Yan, Lin
supporting information, (2020/03/25)
N-(4-Tert-butylphenyl)-4-(3-chloropyridin-2-yl) piperazine-1-carboxamide (BCTC) is a potent and extensively studied urea-based TRPV1 antagonist. Although BCTC was effective in alleviating chronic pain in rats, it showed obvious hyperthermia side-effect an
