174776-68-2

Basic information

• Product Name: 1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI)
• Synonyms: 1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI);(+)-2,3-Dihydro-6-nitro-1H-indene-1-carboxylic acid
• CAS NO: 174776-68-2
• Molecular Formula: C10H9NO4
• Molecular Weight: 0
• Product Categories: AMINOACID
• Mol File: 174776-68-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Density: 1.452
• CAS DataBase Reference: 1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI)(174776-68-2)
• EPA Substance Registry System: 1H-Indene-1-carboxylicacid,2,3-dihydro-6-nitro-,(+)-(9CI)(174776-68-2)

Safety Data

• Hazardous Substances Data: 174776-68-2(Hazardous Substances Data)

Usage

Also known as

(+)-Dihydronepetalactone, Dihydro-6-nitro-2,3-indanedione, 2,3-Dihydro-6-nitro-1H-indene-1-carboxylic acid

Structure

Contains a nitro group

Usage

Commonly used in the synthesis of various pharmaceutical drugs and organic compounds, often utilized as a key intermediate in the production of other chemical compounds.

Upstream product

• 14381-42-1 Indan-1-carboxylic acid 

Relevant articles and documents

DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS

Compounds of formula I: I are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric disorders in a patient in need are also disclosed. Such disorders include depression, bipolar disorder, pain, schizophrenia, obsessive compulsive disorder, addiction, social disorder, attention deficit hyperactivity disorder, an anxiety disorder, autism, a cognitive impairment, or a neuropsychiatric symptom such as apathy, depression, anxiety, psychosis, aggression, agitation, impulse control disorders, and sleep disorders in neurological disorders such as Alzheimer's and Parkinson's diseases.

1,9-ALKANO-BRIDGED-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES

1,9-Alkano-bridged-2,3,4,5-tetrahydro-1H-3-benzazepines and the derivatives thereof, i.e., the compounds of Formula I: STR1 wherein: R is selected from the group consisting of: hydrogen, cyano, lower alkyl, lower alkenyl, and aralkyl;each of R 1, R 2 and R 3 is independently selected from the group consisting of: hydrogen, hydroxy, halo, trifluoromethyl, nitro, amido, lower alkoxy, lower alkyl, and lower alkylthio; andY is lower alkylene having from two to four carbon atoms;and the pharmaceutically acceptable salts thereof, are useful as CNS agents, e.g., as antidepressants, anxiolytics and antihypertensives, and/or as precursors thereto.