174822-06-1

Basic information

• Product Name: Benzenemethanol, 4-(1,1-dimethylethyl)-2-hydroxy-
• CAS NO: 174822-06-1
• Molecular Formula: C11H16O2
• Molecular Weight: 180.247
• Mol File: 174822-06-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-(1,1-dimethylethyl)-2-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-(1,1-dimethylethyl)-2-hydroxy-(174822-06-1)
• EPA Substance Registry System: Benzenemethanol, 4-(1,1-dimethylethyl)-2-hydroxy-(174822-06-1)

Safety Data

• Hazardous Substances Data: 174822-06-1(Hazardous Substances Data)

Upstream product

• 856252-78-3 trifluoro-methanesulfonic acid 5-tert-butyl-2-formyl-phenyl ester 
• 66232-34-6 4-tert-butyl-2-hydroxybenzaldehyde 

Downstream Products

• 5781-02-2 5-(tert-butyl)-2-methylphenol 

Relevant articles and documents

Electrophilicity and nucleophilicity of commonly used aldehydes

The present approach for determining the electrophilicity (E) and nucleophilicity (N) of aldehydes includes a kinetic study of KMNO4 oxidation and NaBH4 reduction of aldehydes. A transition state analysis of the KMNO4 promoted aldehyde oxidation reaction has been performed, which shows a very good correlation with experimental results. The validity of the experimental method has been tested using the experimental activation parameters of the two reactions. The utility of the present approach is further demonstrated by the theoretical versus experimental relationship, which provides easy access to E and N values for various aldehydes and offers an at-a-glance assessment of the chemical reactivity of aldehydes in various reactions. the Partner Organisations 2014.

METHODS FOR TREATING RETINOID RESPONSIVE DISORDERS USING SELECTIVE INHIBITORS OF CYP26A AND CYP26B

The invention provides methods for treating an individual having a retinoid responsive disorder. In one embodiment, a method involves administering to the individual an effective amount of a selective CYP26B inhibitor, the selective CYP26B inhibitor having at least 10-fold selectivity for CYP26B relative to CYP26A. In another embodiment, a method involves administering to the individual an effective amount of a selective CYP26A inhibitor, the selective CYP26A inhibitor having a chemical formula set forth in the specification. The invention further provides screening methods for identifying a selective CYP26A inhibitor or selective CYP26B inhibitor.

Method for producing an unsaturated alcohol

A method for producing an unsaturated alcohol having a chain structure formed by oligomerization of a conjugated alkadiene, which comprises reacting a conjugated alkadiene and water in the presence of carbon dioxide by means of a palladium compound and a phosphorus compound having at least one trivalent phosphorus-oxygen single bond, as catalyst.