17485-31-3Relevant academic research and scientific papers
Copper-catalyzed oxidative decarboxylative arylation of benzothiazoles with phenylacetic acids and α-hydroxyphenylacetic acids with O2 as the sole oxidant
Song, Qiuling,Feng, Qiang,Zhou, Mingxin
supporting information, p. 5990 - 5993 (2014/01/06)
A Cu(II)-catalyzed oxidative decarboxylative synthesis of 2-aryl benzothiazole from phenylacetic acids and α-hydroxyphenylacetic acids has been developed. This reaction proceeds via Cu(II)-catalyzed decarboxylation, C-H bond oxidation, ring-opening, and condensation steps in a one-pot protocol with dioxygen as the sole terminal oxidant. Various functional groups were tolerated under standard conditions, and isolated yields were as high as 95%.
Ru(III)-catalyzed oxidative reaction in ionic liquid: An efficient and practical route to 2-substituted benzothiazoles and their hybrids with pyrimidine nucleoside
Fan, Xuesen,Wang, Yangyang,He, Yan,Zhang, Xinying,Wang, Jianji
experimental part, p. 3493 - 3496 (2010/08/20)
An efficient, practical and environmentally benign synthesis of 2-substituted benzothiazoles was developed through RuCl3-catalyzed oxidative condensation of 2-aminothiophenol with aldehyde in ionic liquid by using air as the oxidant. With this procedure, a series of 2-substituted benzothiazoles and benzothiazole/pyrimidine nucleoside hybrids with antimicrobial activities were efficiently prepared from easily accessible starting materials.
