174851-25-3

Downstream Products

• 942155-68-2 2D-(2,3/4,5)-2,3,4-tri-O-benzyl-5-O-(tert-butyldimethylsilyl)tetrahydroxycyclohexanone 
• 942155-70-6 tert-butyldimethylsilyl 2,3,4-tri-O-benzyl-5a-carba-α-D-galactopyranoside 
• 942155-69-3 tert-butyldimethylsilyl 2,3,4-tri-O-benzyl-6-deoxy-5a-carba-α-L-arabino-hex-5-enopyranoside 
• 942155-74-0 C₂₅H₅₁NO₇ 
• 942155-73-9 (2S,3S,4R)-2-N-benzylamino-1-O-(2,3,4,6-tetra-O-benzyl-5a-carba-α-D-galactopyranosyl)octadecane-1,3,4-triol 
• 942155-72-8 (2S,3S,4R)-1-O-(2,3,4,6-tetra-O-benzyl-5a-carba-α-D-galactopyranosyl)-2-N-benzylamino-3,4-O-isopropylideneoctadecane-1,3,4-triol 
• 942155-71-7 tert-butyldimethylsilyl 2,3,4,6-tetra-O-benzyl-5a-carba-α-D-galactopyranoside 
• 924298-44-2 (1S,2S,3S,4S,5R)-2,3,4-tris(benzyloxy)-5-((benzyloxy)methyl)cyclohexan-1-ol 

Relevant academic research and scientific papers

RCAI-37, 56, 59, 60, 92, 101, and 102, cyclitol and carbasugar analogs of KRN7000: Their synthesis and bioactivity for mouse lymphocytes to produce Th1-biased cytokines

Cyclitol [RCAI-37 (1), 59 (5), 92 (7), and 102 (2)] and carbasugar analogs [RCAI-56 (3), 60 (4), and 101 (6)] of KRN7000 were synthesized through coupling reactions of the corresponding cyclitol or carbasugar derivatives with a cyclic sulfamidate (9) as t

RCAI-56, a carbocyclic analogue of KRN7000: its synthesis and potent activity for natural killer (NK) T cells to preferentially produce interferon-γ

RCAI-56 (3), a carbocyclic analogue of KRN7000 (1) was synthesized through an efficient coupling of a carba-α-d-galactose derivative 11 with cyclic sulfamidate derivative 13 of phytosphingosine to give 15. Carbasugar derivative 11 was prepared by starting

Palladium chloride mediated rearrangement of 6-deoxyhex-5-enopyranosides into cyclohexanones

PdCl2 was found to mediate the Ferrier rearrangement of broad range of substrates catalytically in neutral conditions. In this reaction, the stereoselectivity of newly formed chiral center was controlled by the hydroxyl protective groups on the starting sugar moiety and was rationally explained by the consideration of chair like conformations.