174855-53-9 Usage
Description
TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE is a chemical compound with the molecular formula C18H30N4O2. It is a piperazine derivative that features a tert-butyl group and a carboxylate ester functional group. TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE is characterized by a piperazine ring with an aminomethylphenyl substituent at the 4-position and a tert-butyl group at the nitrogen. It is widely utilized in pharmaceutical research and drug development due to its potential biological activities. However, it is crucial to handle this chemical with caution, as it may present health and environmental risks if not managed properly.
Uses
Used in Pharmaceutical Research and Drug Development:
TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and functional groups contribute to its potential biological activities, making it a valuable component in the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE is used as a building block for the design and synthesis of novel therapeutic agents. Its versatile chemical properties allow for the creation of diverse molecular structures with potential applications in treating various diseases and conditions.
Used in Chemical Synthesis:
TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE is used as a reagent in various chemical synthesis processes. Its functional groups can be modified or reacted with other molecules to produce a wide range of chemical products with different applications.
Used in Analytical Chemistry:
In analytical chemistry, TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE can be employed as a reference compound or a standard for the development and validation of analytical methods. Its well-defined structure and properties make it suitable for use in calibration and quality control processes.
Used in Research and Development of Bioactive Compounds:
TERT-BUTYL 4-[2-(AMINOMETHYL)PHENYL]PIPERAZINE-1-CARBOXYLATE is used as a starting material or a key intermediate in the research and development of bioactive compounds. Its potential biological activities and chemical properties make it an attractive candidate for the discovery of new therapeutic agents and drug leads.
Check Digit Verification of cas no
The CAS Registry Mumber 174855-53-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,8,5 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 174855-53:
(8*1)+(7*7)+(6*4)+(5*8)+(4*5)+(3*5)+(2*5)+(1*3)=169
169 % 10 = 9
So 174855-53-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H25N3O2/c1-16(2,3)21-15(20)19-10-8-18(9-11-19)14-7-5-4-6-13(14)12-17/h4-7H,8-12,17H2,1-3H3
174855-53-9Relevant articles and documents
INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7)
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Paragraph 196; 201-202, (2015/12/24)
The present invention provides novel compounds described herein, such as of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of cyclin-dependent kinase 7 (CDK7), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.
Substituted aryl piperazines as neurokinin antagonists
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, (2008/06/13)
Disclosed are substituted aryl piperazines of Formula I STR1 are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis. In particular compounds of Formula I are shown to be neurokinin antagonists.
