174885-31-5

Basic information

• Product Name: 5-[(4-ACETYLPHENYL)AMINO]-5-OXOPENTANOIC ACID
• Synonyms: 5-[(4-ACETYLPHENYL)AMINO]-5-OXOPENTANOIC ACID;4'-ACETYLGLUTARANILIC ACID;5-[(4-acetylphenyl)amino]-5-keto-valeric acid;5-[(4-ethanoylphenyl)amino]-5-oxo-pentanoic acid;CBDivE_008604;CBKinase1_002349;CBKinase1_014749;ST5445671
• CAS NO: 174885-31-5
• Molecular Formula: C13H15NO4
• Molecular Weight: 249.2625
• Mol File: 174885-31-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-[(4-ACETYLPHENYL)AMINO]-5-OXOPENTANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(4-ACETYLPHENYL)AMINO]-5-OXOPENTANOIC ACID(174885-31-5)
• EPA Substance Registry System: 5-[(4-ACETYLPHENYL)AMINO]-5-OXOPENTANOIC ACID(174885-31-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 174885-31-5(Hazardous Substances Data)

Relevant articles and documents

Enediyne derivatives useful for the synthesis of conjugates of methyltrithio antitumor agents

This invention describes carrier-drug conjugates prepared from disulfide analogs of the calicheamicin family of potent antitumor antibiotics and their derivatives, as well as similar analogs from related antitumor antibiotics such as the esperamicins. The carrier can be an antibody, growth factor, or steroid which targets an undesired population of cells, such as those of a tumor. Whole protein carriers as well as their antigen-recognizing fragments and their chemically or genetically manipulated counterparts are useful for the targeting portion of the conjugates. This invention includes compounds required for the synthesis of these conjugates, appropriate pharmaceutical compositions of the carrier-drug conjugates, and their method of use.