174892-31-0Relevant academic research and scientific papers
Investigation of a novel molecular descriptor for the lead optimization of 4-aminoquinazolines as vascular endothelial growth factor receptor-2 inhibitors: Application for quantitative structure-activity relationship analysis in lead optimization
Kawakami, Joel K.,Martinez, Yannica,Sasaki, Brandi,Harris, Melissa,Kurata, Wendy E.,Lau, Alan F.
, p. 1371 - 1375 (2011)
We investigated the use of infrared vibrational frequency of ligands as a potential novel molecular descriptor in three different molecular target and chemical series. The vibrational energy of a ligand was approximated from the sum of infrared (IR) absor
