174908-78-2

Basic information

• Product Name: (S)-(1,1,4,4-<2H>4)-2-hydroxy-2-methyl-1,4-butane-bis-(toluene-4-sulphonate)
• Synonyms: (S)-(1,1,4,4-<2H>4)-2-hydroxy-2-methyl-1,4-butane-bis-(toluene-4-sulphonate)
• CAS NO: 174908-78-2
• Molecular Weight: 432.496
• Mol File: 174908-78-2.mol

Chemical Properties

• CAS DataBase Reference: (S)-(1,1,4,4-<2H>4)-2-hydroxy-2-methyl-1,4-butane-bis-(toluene-4-sulphonate)(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(1,1,4,4-<2H>4)-2-hydroxy-2-methyl-1,4-butane-bis-(toluene-4-sulphonate)(174908-78-2)
• EPA Substance Registry System: (S)-(1,1,4,4-<2H>4)-2-hydroxy-2-methyl-1,4-butane-bis-(toluene-4-sulphonate)(174908-78-2)

Safety Data

• Hazardous Substances Data: 174908-78-2(Hazardous Substances Data)

Upstream product

• 6236-09-5 (S)-citramalic acid 
• 38574-61-7 (R)-2-hydroxy-2-methyl-butan-1,4-dioic acid dimethyl ester 
• 98-59-9 p-toluenesulfonyl chloride 
• 174908-98-6 (2S)-(1,1,4,4-<2H>4)-2-methylbutane-1,2,4-triol 

Relevant articles and documents

Evidence for an insertion-homolysis mechanism for carbon-sulphur bond formation in penicillin biosynthesis; 1. Synthesis of tripeptide probes

Synthesis of four LLD-ACV analogues, in which the valine residue has been replaced by an amino acid containing a stereospecifically deuterated cyclopropane ring, is described.

Stereochemical course of the conversion of α-ketoisocaproate to β-hydroxyisovalerate by soluble, recombinant mammalian 4-hydroxyphenylpyruvate dioxygenase

The stereochemical course of the conversion of α-ketoisocaproate to β-hydroxyisovalerate catalysed by the enzyme 4-hydroxyphenylpyruvate dioxygenase is described.

Stereochemistry of hydroxylation during the conversion of α-ketoisocaproate to β-hydroxyisovalerate by 4-hydroxyphenylpyruvate dioxygenase

4-Hydroxyphenylpyruvate dioxygenase catalyzes the oxidative decarboxylation and hydroxylation of α-ketoisocaproate 1 to β-hydroxyisovalerate 2 with retention of configuration during the hydroxylation step.