174955-57-8

Basic information

• Product Name: 2-(6-AMINO-9H-PURIN-9-YL)-1,4-ANHYDRO-2-DEOXY-L-ARABINITOL
• Synonyms: 2-(6-AMINO-9H-PURIN-9-YL)-1,4-ANHYDRO-2-DEOXY-L-ARABINITOL
• CAS NO: 174955-57-8
• Molecular Formula: C10H13N5O3
• Molecular Weight: 251.245
• Mol File: 174955-57-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(6-AMINO-9H-PURIN-9-YL)-1,4-ANHYDRO-2-DEOXY-L-ARABINITOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-AMINO-9H-PURIN-9-YL)-1,4-ANHYDRO-2-DEOXY-L-ARABINITOL(174955-57-8)
• EPA Substance Registry System: 2-(6-AMINO-9H-PURIN-9-YL)-1,4-ANHYDRO-2-DEOXY-L-ARABINITOL(174955-57-8)

Safety Data

• Hazardous Substances Data: 174955-57-8(Hazardous Substances Data)

Upstream product

• 136025-01-9 (2R,3R,4S)-4-(6-Amino-purin-9-yl)-2-dimethoxymethyl-tetrahydro-furan-3-ol 
• 20701-43-3 2,5-Anhydro-D-xylose dimethyl acetal 3-(4-methylbenzenesulfonate) 
• 89860-19-5 (1R,2R,5R)-2-(dimethoxymethyl)-3,6-dioxabicyclo[3.1.0]hexane 
• 73-24-5 7H-purin-6-ylamine 
• 73-24-5 adenine 

Downstream Products

• 1053295-31-0 (2S,3R,4S)-4-(6-Amino-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-3-ol 

Relevant articles and documents

Studies on the Synthesis and Biological Activities of 4'-(R)-Hydroxy-5'-(S)-hydroxymethyl-tetrahydrofuranyl Purines and Pyrimidines

A series of 4'-(R)-hydroxy-5'-(S)-hydroxymethyl-tetrahydrofuranyl purines and pyrimidines were synthesized by the reaction of 3,4-epoxy-5-(S,trans)-dimethoxymethyl-tetrahydrofuran and nucleobases under the catalysis of potassium tert-butoxide and 18-crown-6.Compounds 6a, 6c and 7b have shown significant inhibition on the growth of HL-60 cells.The phosphotriester and phosphodiester of isonucleoside 8a-d were synthesized and cytotoxic activities were reported.The conformation of isonucleosides in solution was studied by 1H NMR.Key words: isonucleoside; cytotoxicity; anti-HSV type I and HSV type II; conformation; stereochemistry.