17496-31-0Relevant academic research and scientific papers
CLEAVABLE LIPIDS
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Page/Page column 60; 61, (2013/02/27)
Disclosed herein are novel compounds, pharmaceutical compositions comprising such compounds and related methods of their use. The compounds described herein are useful, e.g., as liposomal delivery vehicles to facilitate the delivery of encapsulated polynucleotides to target cells and subsequent iransfection of said target cells, and in certain embodiments are characterized as having one or more properties that afford such compounds advantages relative to other similarly classified lipids.
THE SYNTHESIS AND CHARACTERIZATION OF SOME NEW THIOETHER-IMIDAZOLE CONTAINING LIGANDS.
Bouwman, E.,Driessen, W. L.
, p. 1581 - 1588 (2007/10/02)
Procedures are described involving a convenient condensation of 4(5)-hydroxymethylimidazole or 5-methyl-4-hydroxymethylimidazole with several thiols.The main step, the condensation reaction in refluxing acetic acid, is essentially the same for all ligands
