175027-87-9Relevant academic research and scientific papers
Phosphonic acid and phosphinic acid tripeptides as inhibitors of glutathionylspermidine synthetase
Verbruggen, Christophe,De Craecker, Sofie,Rajan, Padinchare,Jiao, Xian-Yun,Borloo, Marianne,Smith, Keith,Fairlamb, Alan H.,Haemers, Achiel
, p. 253 - 258 (2007/10/03)
A series of phosphonic and phosphinic acid derivatives of glutathione were synthesized as potential inhibitors of glutathionylspermidine synthetase, an essential enzyme in the biosynthesis of trypanothione in trypanosomatids. The compounds showed moderate activity. Copyright
