175135-53-2 Usage
Uses
Used in Pharmaceutical Industry:
5-amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole is used as an intermediate in the synthesis of Binucleine 2 (B387153) for its role in inhibiting the cytokinesis function of the ARK-2 pathway. This makes it a valuable compound in the development of targeted therapies for various diseases and conditions.
As a Highly Isoform-Specific Inhibitor:
In the field of enzyme inhibition, 5-amino-1-(3-chloro-4-fluorophenyl)-4-cyanopyrazole is used as a highly isoform-specific inhibitor of Drosophila Aurora B kinase. This selective inhibition property is crucial for the development of more precise and effective treatments, as it allows for the targeting of specific enzymes without affecting other similar proteins in the body.
Check Digit Verification of cas no
The CAS Registry Mumber 175135-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,1,3 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175135-53:
(8*1)+(7*7)+(6*5)+(5*1)+(4*3)+(3*5)+(2*5)+(1*3)=132
132 % 10 = 2
So 175135-53-2 is a valid CAS Registry Number.
InChI:InChI=1/C11H6F2N2O3/c12-7-3-4-10(8(13)6-7)18-11-9(15(16)17)2-1-5-14-11/h1-6H
175135-53-2Relevant academic research and scientific papers
Smith, Catherine J.,Iglesias-Sigueenza, Francisco Javier,Baxendale, Ian R.,Ley, Steven V.
, p. 2758 - 2761 (2007)
A new approach to the synthesis of 5-amino-4-cyanopyrazoles has been developed, utilising a novel flow microwave device. These products are then converted by a batch mode microwave process to structurally more complex dimeric and 'mixed' pyrazolopyrimidine structures. The Royal Society of Chemistry.
