175140-22-4

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 175140-14-4 N-(1-Ethyl-propyl)-2-methyl-N-(2,4,6-trimethyl-phenyl)-pyrimidine-4,5,6-triamine 

Downstream Products

• 351380-95-5 6-(1-Ethyl-propylamino)-2,7-dimethyl-9-(2,4,6-trimethyl-phenyl)-7,9-dihydro-purin-8-one 

Relevant academic research and scientific papers

Corticotropin releasing factor antagonists

Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes fo

CRF receptor antagonists and methods relating thereto

Compounds are disclosed which have utility in the treatment of a variety of disorders, including the treatment of disorders manifesting hypersecretion of CRF in a warm-blooded animals, including stroke. The compounds of this invention have the following structures: wherein n, m, R, R1, R2, X and Ar are as defined herein, including stereoisomes and pharmaceutically acceptable salts thereof.

CORTICOTROPIN RELEASING FACTOR ANTAGONISTS

Corticotropin-releasing factor (CRF) antagonists having formulae (I), (II) or (III) wherein the dashed lines, A, B, Y, Z, G, R. sub.3, R. sub.4, R. sub.5, R 6, R 16 and R 17 are as defined in the description, and processes for preparing them. These compou