Cas 175140-52-0,3-Pyridinecarboxylic acid, 4-chloro-6-methyl-2-(2,4,6-trimethylphenoxy)-, methyl ester, 1-oxide

175140-52-0

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Basic information

Product Name: 3-Pyridinecarboxylic acid, 4-chloro-6-methyl-2-(2,4,6-trimethylphenoxy)-, methyl ester, 1-oxide
Synonyms:
CAS NO:175140-52-0
Molecular Formula: C17H18ClNO4
Molecular Weight: 335.787
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 3-Pyridinecarboxylic acid, 4-chloro-6-methyl-2-(2,4,6-trimethylphenoxy)-, methyl ester, 1-oxide(CAS DataBase Reference)
NIST Chemistry Reference: 3-Pyridinecarboxylic acid, 4-chloro-6-methyl-2-(2,4,6-trimethylphenoxy)-, methyl ester, 1-oxide(175140-52-0)
EPA Substance Registry System: 3-Pyridinecarboxylic acid, 4-chloro-6-methyl-2-(2,4,6-trimethylphenoxy)-, methyl ester, 1-oxide(175140-52-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 175140-52-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 175140-52-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,1,4 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 175140-52:
(8*1)+(7*7)+(6*5)+(5*1)+(4*4)+(3*0)+(2*5)+(1*2)=120
120 % 10 = 0
So 175140-52-0 is a valid CAS Registry Number.

175140-52-0Upstream product

175140-52-0Downstream Products

175140-59-7 4-chloro-6-methyl-2-(2,4,6-trimethyl-phenoxy)-nicotinic acid methyl ester

175140-52-0Relevant academic research and scientific papers

Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists

Chen, Yuhpyng L.,Braselton, John,Forman, James,Gallaschun, Randall J.,Mansbach, Robert,Schmidt, Anne W.,Seeger, Thomas F.,Sprouse, Jeff S.,Tingley III, F. David,Winston, Elizabeth,Schulz, David W.

, p. 1377 - 1384 (2008/09/20)

A series of 2-aryloxy-4-alkoxy-pyridines (1) was identified as novel, selective, and orally active antagonists of the corticotropin-releasing factor 1 (CRF1) receptor. Among these, compound 2 (CP-316311) is a potent and selective CRF1/sub

2-Aryloxy-4-alkylaminopyridines: Discovery of novel corticotropin-releasing factor 1 antagonists

Chen, Yuhpyng L.,Obach, R. Scott,Braselton, John,Corman, Michael L.,Forman, James,Freeman, Jody,Gallaschun, Randall J.,Mansbach, Robert,Schmidt, Anne W.,Sprouse, Jeffrey S.,Tingley III, F. David,Winston, Elizabeth,Schulz, David W.

, p. 1385 - 1392 (2008/09/20)

An orally active clinical candidate of corticotropin-releasing factor 1 (CRF1) antagonist 1 showed a significant positive food effect in dog and human after oral administration. Efforts to address the food effect issue led us to explore and dis

Corticotropin releasing factor antagonists

-

, (2008/06/13)

Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes fo

Method of treating heart failure

-

, (2008/06/13)

This invention relates to method for treating a mammal which presents with heart failure comprising administering to a mammal a therapeutically effective amount of wherein 4-(1-ethyl-propoxy)-3,6-dimethyl-2-(2,4,6-trimethyl-phenoxy)-pyridine and (3,6-dime

Use of 3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-pyridines for treating heart failure

-

, (2008/06/13)

This invention relates to treatments for a mammal which presents with heart failure comprising administering to a mammal a therapeutically effective amount of wherein 4-(1-ethyl-propoxy)-3,6-dimethyl-2-(2,4,6-trimethyl-phenoxy)-pyridine and (3,6-dimethyl-

CORTICOTROPIN RELEASING FACTOR ANTAGONISTS

-

, (2008/06/13)

Corticotropin-releasing factor (CRF) antagonists having formulae (I), (II) or (III) wherein the dashed lines, A, B, Y, Z, G, R. sub.3, R. sub.4, R. sub.5, R 6, R 16 and R 17 are as defined in the description, and processes for preparing them. These compou

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