175140-54-2Relevant academic research and scientific papers
Synthesis and SAR of 2-aryloxy-4-alkoxy-pyridines as potent orally active corticotropin-releasing factor 1 receptor antagonists
Chen, Yuhpyng L.,Braselton, John,Forman, James,Gallaschun, Randall J.,Mansbach, Robert,Schmidt, Anne W.,Seeger, Thomas F.,Sprouse, Jeff S.,Tingley III, F. David,Winston, Elizabeth,Schulz, David W.
, p. 1377 - 1384 (2008/09/20)
A series of 2-aryloxy-4-alkoxy-pyridines (1) was identified as novel, selective, and orally active antagonists of the corticotropin-releasing factor 1 (CRF1) receptor. Among these, compound 2 (CP-316311) is a potent and selective CRF1/sub
Corticotropin releasing factor antagonists
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, (2008/06/13)
Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes fo
CORTICOTROPIN RELEASING FACTOR ANTAGONISTS
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, (2008/06/13)
Corticotropin-releasing factor (CRF) antagonists having formulae (I), (II) or (III) wherein the dashed lines, A, B, Y, Z, G, R. sub.3, R. sub.4, R. sub.5, R 6, R 16 and R 17 are as defined in the description, and processes for preparing them. These compou
