175165-89-6Relevant articles and documents
Total syntheses of Be-12406 a and its C(8)-Vinyl analog
Hosoya, Takamitsu,Takashiro, Eiji,Yamamoto, Yasuko,Matsumoto, Takashi,Suzuki, Keisuke
, p. 397 - 414 (2007/10/02)
Total syntheses of BE-12406 A (3a) and its C(8)-vinyl analog (3c) are described. The key step is the selective O-glycosylation of naphthol (4)with L-rhamnopyranosyl fluoride (5) by employing Cp2HfCl2-AgClO4 in fluorobenzene at -20°C in the presence of a hindered base, 2,6-di-t-butyl-4-methylpyridine (12), affording O-glycoside (11) in good yield.