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N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE, also known as N-Hydroxy-2-(2-thienylsulfonyl)ethanimidamide, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which includes a thienylsulfonyl group and an ethanimidamide moiety. N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE plays a significant role in the development of class II human histone deacetylase inhibitors, which are important for various therapeutic applications.

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  • 175201-96-4 Structure
  • Basic information

    1. Product Name: N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE
    2. Synonyms: N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE;N'-hydroxy-2-(2-thienylsulphonyl)ethanimidamide;(THIEN-2-YLSULFONYL)ACETAMIDE OXIME;N-Hydroxy-2-(thiophen-2-ylsulfonyl)acetiMidaMide
    3. CAS NO:175201-96-4
    4. Molecular Formula: C6H8N2O3S2
    5. Molecular Weight: 220.27
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 175201-96-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: DCM, DMSO, Ethyl Acetate, Methanol
    9. CAS DataBase Reference: N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE(175201-96-4)
    11. EPA Substance Registry System: N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE(175201-96-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 175201-96-4(Hazardous Substances Data)

175201-96-4 Usage

Uses

Used in Pharmaceutical Industry:
N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE is used as an intermediate in the synthesis of class II human histone deacetylase inhibitors for their potential therapeutic applications in treating various diseases, including cancer and neurological disorders. The compound's unique structure allows for the development of novel inhibitors that can modulate the activity of histone deacetylases, thereby affecting gene expression and cellular processes.
Used in Cancer Treatment:
N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE is used as a key component in the development of histone deacetylase inhibitors, which are employed as anticancer agents. These inhibitors can modulate the activity of histone deacetylases, leading to changes in gene expression that can inhibit tumor growth and progression. By targeting specific histone deacetylases, these inhibitors can potentially be used to treat various types of cancer, including solid tumors and hematological malignancies.
Used in Neurological Disorders:
In addition to its applications in cancer treatment, N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE is also used in the development of histone deacetylase inhibitors for the treatment of neurological disorders. These inhibitors can modulate the epigenetic landscape of neurons, potentially leading to the amelioration of symptoms and disease progression in conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis.
Used in Drug Delivery Systems:
N'-HYDROXY-2-(2-THIENYLSULFONYL)ETHANIMIDAMIDE can be utilized in the development of novel drug delivery systems to improve the bioavailability and therapeutic outcomes of histone deacetylase inhibitors. By employing various organic and metallic nanoparticles as carriers, the compound can be effectively delivered to target cells, enhancing its efficacy and minimizing potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 175201-96-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 175201-96:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*1)+(2*9)+(1*6)=124
124 % 10 = 4
So 175201-96-4 is a valid CAS Registry Number.

175201-96-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N'-hydroxy-2-thiophen-2-ylsulfonylethanimidamide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:175201-96-4 SDS

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