175203-08-4

Basic information

• Product Name: 4-(4-CHLOROPHENYL)PYRIMIDINE-2-THIOL
• Synonyms: ART-CHEM-BB B020820;BUTTPARK 25\04-71;4-(4-CHLOROPHENYL)PYRIMIDINE-2-THIOL;AKOS B020820;SALOR-INT L481459-1EA;4-(4-Chlorophenyl)-2-mercaptopyrimidine;4-(4-Chlorophenyl)-2-MercaptopyriMidine4-(4-chlorophenyl)pyriMid;4-(4-Chlorophenyl)-2-MercaptopyriMidine4-(4-chlorophenyl)pyriMidine-2-thiol
• CAS NO: 175203-08-4
• Molecular Formula: C₁₀H₇ClN₂S
• Molecular Weight: 222.69
• Mol File: 175203-08-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 210 °C
• Boiling Point: 357.1 °C at 760 mmHg
• Flash Point: 169.8 °C
• Appearance: /
• Density: 1.35 g/cm³
• Vapor Pressure: 2.79E-05mmHg at 25°C
• Refractive Index: 1.674
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(4-CHLOROPHENYL)PYRIMIDINE-2-THIOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-CHLOROPHENYL)PYRIMIDINE-2-THIOL(175203-08-4)
• EPA Substance Registry System: 4-(4-CHLOROPHENYL)PYRIMIDINE-2-THIOL(175203-08-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 175203-08-4(Hazardous Substances Data)

Usage

General Description

4-(4-Chlorophenyl)pyrimidine-2-thiol, also known as CCPMT, is a chemical compound with the formula C11H7ClN2S. It is a pyrimidine derivative with a 4-chlorophenyl substituent and a thiol functional group attached to the 2-position of the pyrimidine ring. 4-(4-Chlorophenyl)pyrimidine-2-thiol has been studied for its potential use in pharmaceutical applications, particularly in the development of new drugs. It has been reported to possess antimicrobial, antifungal, and anticancer properties, making it a promising candidate for further research and development. Additionally, 4-(4-Chlorophenyl)pyrimidine-2-thiol can also be used as a building block in organic synthesis for the preparation of various other compounds.

InChI:InChI=1/C10H7ClN2S/c11-8-3-1-7(2-4-8)9-5-6-12-10(14)13-9/h1-6H,(H,12,13,14)

Upstream product

• 67382-35-8 (2E)-3-(dimethylamino)-1-(4-chlorophenyl)prop-2-en-1-one 

Downstream Products

• 434941-55-6 4-(4-chlorophenyl)-2-(methylthio)pyrimidine 
• 568591-74-2 [1-({[4-(4-chlorophenyl)-2-pyrimidinyl]sulfanyl}methyl)cyclobutyl]methanol 

Relevant articles and documents

METHODS FOR TREATING OR PREVENTING AN INFLAMMATORY OR METABOLIC CONDITION OR INHIBITING JNK

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Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto

Compounds having activity as inhibitors of the JNK pathway are disclosed. The compounds of this invention are anilinopyrimidine derivatives having the following structure: wherein R1 through R6 are as defined herein. Such compounds have utility in the treatment of a wide range of conditions that are responsive to inhibition of the JNK pathway. Thus, methods of treating such conditions are also disclosed, as are pharmaceutical compositions containing one or more compounds of the above compounds.