175203-87-9 Usage
Uses
Used in Pharmaceutical Industry:
6-(TRIFLUOROMETHOXY)-4-QUINOLINOL is used as a pharmaceutical intermediate for its potential role in the synthesis of various medicinal compounds. The trifluoromethoxy group can enhance the bioactivity and pharmacokinetic properties of the resulting drugs.
Used in Antimicrobial Applications:
6-(TRIFLUOROMETHOXY)-4-QUINOLINOL is utilized as an antimicrobial agent, effective against a range of bacteria. Its unique structure allows it to target and disrupt essential cellular processes in bacteria, thereby inhibiting their growth and proliferation.
Used in Antifungal Applications:
6-(TRIFLUOROMETHOXY)-4-QUINOLINOL is employed as an antifungal agent, exhibiting activity against various fungal species. Its ability to interfere with fungal cell metabolism and membrane integrity contributes to its antifungal efficacy.
Used in Organic Synthesis:
6-(TRIFLUOROMETHOXY)-4-QUINOLINOL is used as a building block in organic synthesis, enabling the creation of novel compounds with diverse applications. The trifluoromethoxy group can participate in various chemical reactions, facilitating the synthesis of complex organic molecules.
Used in Material Development:
6-(TRIFLUOROMETHOXY)-4-QUINOLINOL is utilized in the development of new materials, such as polymers and coatings, due to its unique properties. The trifluoromethoxy group can impart specific characteristics, such as enhanced stability, solubility, or reactivity, to the resulting materials.
Check Digit Verification of cas no
The CAS Registry Mumber 175203-87-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 175203-87:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*3)+(2*8)+(1*7)=129
129 % 10 = 9
So 175203-87-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H6F3NO2/c11-10(12,13)16-6-1-2-8-7(5-6)9(15)3-4-14-8/h1-5H,(H,14,15)
175203-87-9Relevant academic research and scientific papers
PAPD5 INHIBITORS AND METHODS OF USE THEREOF
-
, (2020/11/03)
The present application provides compounds that are PAPD5 inhibitors and are useful in treating a variety of conditions such as cancer, telomere diseases, and aging-related and other degenerative disorders.
Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities
Madrid, Peter B.,Sherrill, John,Liou, Ally P.,Weisman, Jennifer L.,DeRisi, Joseph L.,Guy, R. Kiplin
, p. 1015 - 1018 (2007/10/03)
A simple two-step synthesis method was used to make 51 B-ring-substituted 4-hydroxyquinolines allowing analysis of the effect of ring substitutions on inhibition of growth of chloroquine sensitive and resistant strains of Plasmodium falciparum, the dominant cause of malaria morbidity. Substituted quinoline rings other than the 7-chloroquinoline ring found in chloroquine were found to have significant activity against the drug-resistant strain of P. falciparum W2.
