175204-22-5

Usage

Uses

Used in Organic Synthesis:
5-CHLORO-6-FLUOROBENZO-2,1,3-THIADIAZOLE is used as a key intermediate in organic synthesis for its ability to contribute to the formation of complex molecular structures. Its presence in reactions can lead to the development of new organic compounds with diverse applications.
Used in Materials Science:
In the field of materials science, 5-CHLORO-6-FLUOROBENZO-2,1,3-THIADIAZOLE is utilized as a component in the design and synthesis of novel materials. Its unique properties allow it to enhance the performance characteristics of these materials, such as their stability, conductivity, or other functional attributes.
Used in Pharmaceutical Research:
5-CHLORO-6-FLUOROBENZO-2,1,3-THIADIAZOLE is employed as a building block in pharmaceutical research for the development of new drugs. Its structural features make it a promising candidate for the creation of pharmaceutical agents with potential therapeutic effects.
Used in Agrochemical Development:
5-CHLORO-6-FLUOROBENZO-2,1,3-THIADIAZOLE is also used in agrochemical research as a precursor to develop new pesticides or other agrochemicals. Its unique structure can contribute to the effectiveness of these products in agricultural applications.
Overall, 5-CHLORO-6-FLUOROBENZO-2,1,3-THIADIAZOLE's versatility in various scientific domains highlights its importance in the synthesis and development of a wide range of products and materials.

InChI:InChI=1/C6H2ClFN2S/c7-3-1-5-6(2-4(3)8)10-11-9-5/h1-2H

Upstream product

• 139512-70-2 4-chloro-5-fluorobenzene-1,2-diamine 

Relevant academic research and scientific papers

ORGANIC SEMICONDUCTING COMONOMER

A comonomer comprising: wherein W is selected from the group consisting of: S, Se, O, and N-Q; and Q is selected from the group consisting of: a straight-chain or branched carbyl, silyl, or hydrocarbyl, a branched or cyclic alkyl with 1 to 30 atoms, a fused substituted aromatic ring, and a fused unsubstituted aromatic ring. In this comonomer, A and B are independently selected from the group consisting of: H, Br, an aryl group, and a heteroaryl group.

Chlorination: Vs. fluorination: A study of halogenated benzo [c] [1,2,5]thiadiazole-based organic semiconducting dots for near-infrared cellular imaging

Red/near-infrared organic dyes are becoming increasingly widespread in biological applications. However, designing these dyes with long-wavelength emission, large Stokes shifts, and high fluorescence quantum efficiency is still a very challenging task. In this work, five donor-acceptor (D-A) red/near-infrared fluorophores based on different chlorinated/fluorinated benzo[c][1,2,5]thiadiazole units are designed and synthesized. The photophysical, theoretical calculations, and electrochemical properties explored in this study have proved that the introducing of chlorine atoms will lead to a lower HOMO level, stronger steric hindrance, and a relatively lower quantum yield in solutions. When the organic dots are fabricated, the chlorinated dots demonstrate much higher fluorescence quantum yield, larger Stokes shift, and better photostability than that of the fluorinated dots. After labeling A549 cells, all the chlorinated/fluorinated dots exhibit high red emission intensities. All these results indicated that the subtle change in the halogen atom of the benzo[c][1,2,5]thiadiazole unit is a unique method to tune the photophysical properties of those materials, and also provides good guidelines to design highly efficient red/near-infrared molecules for cellular imaging applications.