175205-61-5 Usage
Uses
Used in Pharmaceutical Industry:
3-(CHLOROMETHYL)-5-(2-METHOXYPHENYL)-1,2,4-OXADIAZOLE is used as a potential anti-cancer agent for its ability to target various types of cancer cells. Its structure allows for the possibility of modulating signaling pathways associated with cancer progression, offering a new avenue for therapeutic intervention.
Used in Anti-Inflammatory Applications:
In the field of anti-inflammatory research, 3-(CHLOROMETHYL)-5-(2-METHOXYPHENYL)-1,2,4-OXADIAZOLE is utilized for its potential to mitigate inflammation, which could be beneficial in treating a range of inflammatory conditions.
Used in Antimicrobial Applications:
3-(CHLOROMETHYL)-5-(2-METHOXYPHENYL)-1,2,4-OXADIAZOLE is employed as an antimicrobial agent, leveraging its chemical properties to combat microbial infections, which is particularly important in the context of increasing antibiotic resistance.
Used in Medicinal Chemistry Research:
As a chemical intermediate, 3-(CHLOROMETHYL)-5-(2-METHOXYPHENYL)-1,2,4-OXADIAZOLE is used in the synthesis of other bioactive compounds, contributing to the development of new drugs with improved pharmacological profiles.
Used in Drug Design and Development:
3-(CHLOROMETHYL)-5-(2-METHOXYPHENYL)-1,2,4-OXADIAZOLE is utilized in the design of novel drug candidates, taking advantage of its unique structural elements to create molecules with enhanced therapeutic potential and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 175205-61-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,0 and 5 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 175205-61:
(8*1)+(7*7)+(6*5)+(5*2)+(4*0)+(3*5)+(2*6)+(1*1)=125
125 % 10 = 5
So 175205-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H9ClN2O2/c1-14-8-5-3-2-4-7(8)10-12-9(6-11)13-15-10/h2-5H,6H2,1H3
175205-61-5Relevant academic research and scientific papers
Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists
Elzein, Elfatih,Kalla, Rao,Li, Xiaofen,Perry, Thao,Parkhill, Eric,Palle, Venkata,Varkhedkar, Vaibahv,Gimbel, Art,Zeng, Dewan,Lustig, David,Leung, Kwan,Zablocki, Jeff
, p. 302 - 306 (2007/10/03)
A series of new 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)- xanthine derivatives as A2B-AdoR antagonists have been synthesized and evaluated for their binding affinities for the A2B, A 1, A2A, and A3-AdoRs. 8-(1-((3-phenyl-1,2,4- oxadiazol-5-yl)methyl)-1H-pyrazol-4-yl)-1,3-dipropyl-1H-purine-2,6(3H,7H)-dione (4) displayed high affinity (Ki = 1 nM) and selectivity for the A2B-AdoR versus A1, A2A, and A 3-AdoRs (A1/A2B, A2A/A2B, and A3/A2B selectivity ratios of 370, 1100, and 480, respectively). The synthesis and SAR of this novel class of compounds are presented herein.
