175210-88-5Relevant articles and documents
Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1β converting enzyme.
Golec, Julian M. C.,Mullican, Michael D.,Murcko, Mark A.,Wilson, Keith P.,Kay, David P.,Jones, Stuart D.,Murdoch, Robert,Bemis, Guy W.,Raybuck, Scott A.,Luong, Yu-Ping,Livingston, David J.
, p. 2181 - 2186 (2007/10/03)
Pyridone derivatives, especially with 6-aryl substituents, have been shown to be useful P2-P3 peptidomimetic scaffolds for the design of potent inhibitors of ICE.