175214-20-7

Basic information

• Product Name: Cbz-Tyr(MPM)-OMe
• Synonyms: Cbz-Tyr(MPM)-OMe
• CAS NO: 175214-20-7
• Molecular Weight: 449.503
• Mol File: 175214-20-7.mol

Chemical Properties

• CAS DataBase Reference: Cbz-Tyr(MPM)-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Cbz-Tyr(MPM)-OMe(175214-20-7)
• EPA Substance Registry System: Cbz-Tyr(MPM)-OMe(175214-20-7)

Safety Data

• Hazardous Substances Data: 175214-20-7(Hazardous Substances Data)

Upstream product

• 1164-16-5 Z-L-Tyr-OH 
• 13512-31-7 N-(benzyloxycarbonyl)-L-tyrosine methyl ester 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 187328-92-3 Boc-Tyr(Bn)-Tyr(MPM)-OMe 
• 27513-48-0 N-(tert-butoxycarbonyl)-L-tyrosyl-L-tyrosine methyl ester 
• 175214-21-8 Tyr(MPM)-OMe 

Relevant articles and documents

Pd/C-catalyzed chemoselective hydrogenation in the presence of a phenolic MPM protective group using pyridine as a catalyst poison

Employment of a Pd/C-pyridine combination as a catalyst is a very useful method for the selective removal (hydrogenolysis) of phenolic O-benzyl, N-Cbz and benzyl ester protective groups and for the selective hydrogenation of nitro and olefin functions of phenol derivatives protected with the MPM group. These discriminatory results are apparently attributable to the effect of pyridine. The MPM group could be extensively applied to chemoselective hydrogenation as a protective group for phenolic hydroxyl functions.