175224-23-4

Basic information

• Product Name: Z-L-(αMe)Val-F
• Synonyms: Z-L-(αMe)Val-F
• CAS NO: 175224-23-4
• Molecular Weight: 267.3
• Mol File: 175224-23-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Z-L-(αMe)Val-F(CAS DataBase Reference)
• NIST Chemistry Reference: Z-L-(αMe)Val-F(175224-23-4)
• EPA Substance Registry System: Z-L-(αMe)Val-F(175224-23-4)

Safety Data

• Hazardous Substances Data: 175224-23-4(Hazardous Substances Data)

Upstream product

• 137584-46-4 2-benzyloxy-4-isopropyl-4-methyl-5(4H)-oxazolone 
• 137584-40-8 (S)-(+)-2-benzyloxycarbonylamino-2,3-dimethylbutanoic acid 

Downstream Products

• 182688-22-8 Z-[L-(αMe)Val]3-OtBu 
• 182688-23-9 (S)-2-{(S)-2-[(S)-2-((S)-2-Benzyloxycarbonylamino-2,3-dimethyl-butyrylamino)-2,3-dimethyl-butyrylamino]-2,3-dimethyl-butyrylamino}-2,3-dimethyl-butyric acid tert-butyl ester 
• 182688-24-0 Z-[L-(αMe)Val]5-OtBu 
• 182688-25-1 (S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Benzyloxycarbonylamino-2,3-dimethyl-butyrylamino)-2,3-dimethyl-butyrylamino]-2,3-dimethyl-butyrylamino}-2,3-dimethyl-butyrylamino)-2,3-dimethyl-butyrylamino]-2,3-dimethyl-butyric acid tert-butyl ester 
• 175224-24-5 Z-[L-(αMe)Val]7-OtBu 
• 175224-25-6 Z-[L-(αMe)Val]8-OtBu 
• 1605397-55-4 Cbz-L-α-methylvaline-L-Val-Aib₄-GlyNH₂ 
• 1605397-56-5 Cbz-L-α-methylvaline-t-Leu-Aib₄-GlyNH₂ 
• 1273555-65-9 Z-(αMe)ValAibAib**AibAibAib**AibAibAib**AibOtBu 
• 1273555-61-5 C₃₄⁽¹³⁾C₄H₆₁N₇O₁₀ 
• 1273555-54-6 C₂₄⁽¹³⁾C₂H₄₀N₄O₇ 
• 1273555-55-7 Z-(αMe)ValAibAib**AibAibAib**AibOtBu 
• 1273555-52-4 Z-(αMe)ValAibAib**OtBu 
• 182688-21-7 Z-[L-(αMe)Val]2-OtBu 

Relevant articles and documents

Thionoglycine as a multifunctional spectroscopic reporter of screw-sense preference in helical foldamers

A single thionoglycine (glycine thioamide, -HNCH2C(S)-) residue inserted into a peptide foldamer provides both a pair of germinal protons for use as a 1H NMR stereochemical probe and a chromophore giving rise to a well defined Cotton

Induction of unexpected left-handed helicity by an N-terminal L -amino acid in an otherwise achiral peptide chain

Peptide helices containing L-amino acids are typically right-handed. Exceptions are peptide helices containing the achiral amino acids 2-aminoisobutyric acid and glycine with a single chiral amino acid at the Nterminus. These helices are left-handed when the N-terminal residue is a common tertiary proteinogenic amino acid, such as L-valine (see picture, left), but right-handed when the N-terminal residue is the quaternary amino acid L-α-methylvaline (right). Copyright

Peptide Helices as Rigid Molecular Rulers: A Conformational Study of Isotactic Homopeptides from α-Methyl-α-isopropylglycine, n

Terminally blocked, isotactic homopeptides from the sterically demanding α-methylvaline of general formula Y-n-O-t-Bu (Y = Z, pBrBz, Ac; n = 2-8) have been prepared step-by-step in solution and fully characterized.The conformations preferred i