175233-02-0

Basic information

• Product Name: (S)-1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-pyrrolidine-2-carboxylic acid tert-butyl ester
• Synonyms: (S)-1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-pyrrolidine-2-carboxylic acid tert-butyl ester
• CAS NO: 175233-02-0
• Molecular Weight: 346.426
• Mol File: 175233-02-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-pyrrolidine-2-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-pyrrolidine-2-carboxylic acid tert-butyl ester(175233-02-0)
• EPA Substance Registry System: (S)-1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-pyrrolidine-2-carboxylic acid tert-butyl ester(175233-02-0)

Safety Data

• Hazardous Substances Data: 175233-02-0(Hazardous Substances Data)

Upstream product

• 175233-01-9 (R)-N-Benzyloxy-2-bromo-3-hydroxy-propionamide 
• 175233-09-7 (S)-1-((S)-1-Benzyloxycarbamoyl-2-hydroxy-ethyl)-pyrrolidine-2-carboxylic acid tert-butyl ester 

Downstream Products

• 175233-06-4 (S)-1-((S)-1-Benzyloxy-2-oxo-azetidin-3-yl)-pyrrolidine-2-carboxylic acid 

Relevant articles and documents

Synthesis of (S,S)-3-prolylazetidin-2-one: A key component in the synthesis of an HIV gp120 constrained immunogen

The title compound (2) was synthesized in 5 steps from D-serine. In the absence of protection of the carboxyl group, the β-lactam nucleus underwent a facile rearrangement to provide the undesired diazabicyclo[4.3.0]nonane compound, under acidic or basic c