175275-67-9

Upstream product

• 77-78-1 dimethyl sulfate 
• 157848-98-1 4-acetoxy-8-benzyloxy-2-(2,3,4-tri-O-benzyl-β-L-rhamnopyranosyl)-1-naphthol 
• 104495-20-7 2,3,4-tris-O-(phenylmethyl)-α-L-rhamnopyranosyl fluoride 
• 104506-17-4 4-Acetoxy-8-benzyloxy-1-hydroxynaphthalene 
• 210426-02-1 2,3,4-tri-O-benzyl-L-rhamnopyranose 

Relevant academic research and scientific papers

Total syntheses of Be-12406 a and its C(8)-Vinyl analog

Total syntheses of BE-12406 A (3a) and its C(8)-vinyl analog (3c) are described. The key step is the selective O-glycosylation of naphthol (4)with L-rhamnopyranosyl fluoride (5) by employing Cp2HfCl2-AgClO4 in fluorobenzene at -20°C in the presence of a hindered base, 2,6-di-t-butyl-4-methylpyridine (12), affording O-glycoside (11) in good yield.