175276-69-4

Basic information

• Product Name: ETHYL 2-METHYL-5-(4-NITROPHENYL)-3-FUROATE
• Synonyms: ETHYL 2-METHYL-5-(4-NITROPHENYL)-3-FUROATE;Ethyl 2-Methyl-5-(4-nitrophenyl)furan-3-carboxylate
• CAS NO: 175276-69-4
• Molecular Formula: C₁₄H₁₃NO₅
• Molecular Weight: 275.25672
• Mol File: 175276-69-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ETHYL 2-METHYL-5-(4-NITROPHENYL)-3-FUROATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-METHYL-5-(4-NITROPHENYL)-3-FUROATE(175276-69-4)
• EPA Substance Registry System: ETHYL 2-METHYL-5-(4-NITROPHENYL)-3-FUROATE(175276-69-4)

Safety Data

• Hazardous Substances Data: 175276-69-4(Hazardous Substances Data)

Upstream product

• 72771-97-2 ethyl 2-acetyl-4-(4-nitrophenyl)-4-oxobutanoate 
• 2009-97-4 ethyl 2-diazo-3-oxobutanoate 
• 74812-79-6 1-(4-nitrophenyl)-1-trimethylsilyloxyethylene 
• 100-19-6 (4-nitrophenyl)ethanone 
• 41780-82-9 4-methyl-N'-(1-(4-nitrophenyl)ethylidene)benzenesulfonohydrazide 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 175276-70-7 ethyl 5-(4-aminophenyl)-2-methyl-3-furanecarboxylate 

Relevant articles and documents

Copper-Catalyzed Coupling of 2-Siloxy-1-alkenes and Diazocarbonyl Compounds: Approach to Multisubstituted Furans, Pyrroles, and Thiophenes

We report herein copper(II)-catalyzed cyclization reactions of silyl enol ethers derived from methyl ketones with α-diazo-β-ketoesters or α-diazoketones to afford 2-siloxy-2,3-dihydrofuran derivatives or 2,3,5-trisubstituted furans, respectively, under mild conditions. The former cyclization products serve as versatile 1,4-diketone surrogates, allowing facile preparation of 2,3,5-trisubstituted furans, pyrroles, and thiophenes.

Ionic liquid as catalyst and reaction medium: A Simple and Efficient Procedure for Paal-Knorr furan synthesis

The ionic liquid 1-butyl-3-methyl-imidazolium hydrogen sulfate, [bmim]HSO4, efficiently catalyzes Paal-Knorr furan synthesis without any organic solvent. A wide range of aliphatic and aromatic 1,4-diketones easily undergo condensations to form furan derivatives, providing a general and convenient procedure. The Paal-Knorr reaction of ester-substituted 1,4-diketones is first reported. The ionic liquid can be recovered and reused for subsequent runs without any appreciable loss of efficiency.