175277-44-8

Usage

Uses

Used in Pharmaceutical Industry:
5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME is used as a building block for the synthesis of new chemical entities in drug development. Its unique structure and functional groups contribute to the creation of innovative pharmaceutical compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical field, 5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME is utilized in the development of herbicides and pesticides. Its chemical properties allow for the design of effective agents that can target and control unwanted plant species or pests, thereby enhancing crop protection and yield.
Used in Materials Science:
5-(TRIFLUOROMETHYL)PYRIDINE-2-CARBOXAMIDE OXIME serves as a key component in the production of functional materials. Its incorporation into various materials can impart specific properties, such as improved stability, reactivity, or selectivity, making it valuable for the development of advanced materials with specialized applications.

InChI:InChI=1/C7H6F3N3O/c8-7(9,10)4-1-2-5(12-3-4)6(11)13-14/h1-3,14H,(H2,11,13)

Upstream product

• 95727-86-9 2-cyano-5-trifluoro-methylpyridine 

Relevant academic research and scientific papers

INHIBITOR COMPOUNDS

The disclosure relates to heterocyclic compounds and methods for their preparation. The disclosure provides compounds that may have beneficial therapeutic activity in the treatment of a disease or condition mediated by excessive or otherwise undesirable Des1 and/or fibrotic activity.

5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein

The HIV-1 nucleocapsid (NC) protein is a small basic DNA and RNA binding protein that is absolutely necessary for viral replication and thus represents a target of great interest to develop new anti-HIV agents. Moreover, the highly conserved sequence offers the opportunity to escape the drug resistance (DR) that emerged following the highly active antiretroviral therapy (HAART) treatment. On the basis of our previous research, nordihydroguaiaretic acid 1 acts as a NC inhibitor showing moderate antiviral activity and suboptimal drug-like properties due to the presence of the catechol moieties. A bioisosteric catechol replacement approach led us to identify the 5-dihydroxypyrimidine-6-carboxamide substructure as a privileged scaffold of a new class of HIV-1 NC inhibitors. Hit validation efforts led to the identification of optimized analogs, as represented by compound 28, showing improved NC inhibition and antiviral activity as well as good ADME and PK properties.

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

N-phenylcarbamate compound, process for preparing the sasme and biocidal composition for control of harmful organisms

A novel N-phenylcarbamate compound or its salt where possible, which is useful as the active ingredient of a biocidal composition for control of harmful organisms, is represented by the following general formula (I): STR1 wherein R1 is unsubsti