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5-Nitrohexahydropyrimidine-2,4,6-trione hydrate, commonly known as nitrodantoin, is a chemical compound that belongs to the class of nitrofurans. It is primarily used as an antimicrobial agent, particularly for the treatment of urinary tract infections. Nitrodantoin works by inhibiting the synthesis of bacterial DNA, leading to the death of the bacteria. It is known for its low toxicity and is usually well-tolerated by patients, making it a preferred choice for treating infections caused by susceptible bacteria. However, it is essential to use 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE under the supervision of a healthcare professional, as it is associated with potential side effects and can interact with other medications. Overall, 5-Nitrohexahydropyrimidine-2,4,6-trione hydrate is an important chemical in the field of antimicrobial therapy.

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  • 175278-58-7 Structure
  • Basic information

    1. Product Name: 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE
    2. Synonyms: 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE;5-NITROBARBITURIC ACID MONOHYDRATE
    3. CAS NO:175278-58-7
    4. Molecular Formula: C4H5N3O6
    5. Molecular Weight: 191.1
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 175278-58-7.mol
  • Chemical Properties

    1. Melting Point: 208 °C
    2. Boiling Point: 469.7°Cat760mmHg
    3. Flash Point: 237.9°C
    4. Appearance: /
    5. Density: g/cm3
    6. Vapor Pressure: 2.4E-10mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE(175278-58-7)
    12. EPA Substance Registry System: 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE(175278-58-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 175278-58-7(Hazardous Substances Data)

175278-58-7 Usage

Uses

Used in Pharmaceutical Industry:
5-Nitrohexahydropyrimidine-2,4,6-trione hydrate is used as an antimicrobial agent for the treatment of urinary tract infections. It is effective against a wide range of bacteria, including Escherich as well as other susceptible bacteria. Its low toxicity and good patient tolerance make it a preferred choice for treating such infections.
Used in Antimicrobial Therapy:
Nitrodantoin is used as an antimicrobial agent to inhibit the synthesis of bacterial DNA, ultimately leading to the death of the bacteria. This makes it a valuable component in the treatment of infections caused by susceptible bacteria.

Check Digit Verification of cas no

The CAS Registry Mumber 175278-58-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,7 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 175278-58:
(8*1)+(7*7)+(6*5)+(5*2)+(4*7)+(3*8)+(2*5)+(1*8)=167
167 % 10 = 7
So 175278-58-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H3N3O5.H2O/c8-2-1(7(11)12)3(9)6-4(10)5-2;/h1H,(H2,5,6,8,9,10);1H2

175278-58-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-NITROHEXAHYDROPYRIMIDINE-2,4,6-TRIONE HYDRATE

1.2 Other means of identification

Product number -
Other names 5-NITROBARBITURIC ACID MONOHYDRATE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:175278-58-7 SDS

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