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Maleimidocaproic acid hydrazide-HCl, often abbreviated as MIAC, is a versatile chemical compound that plays a significant role in bioconjugation, a process that forms covalent links between two molecules. This acid is particularly useful for modifying proteins, as its hydrazide group can conjugate with aldehydes and ketones in proteins, typically under mildly acidic conditions. Additionally, its maleimide group reacts with the thiol group (-SH) of another molecule, resulting in the formation of a stable thioether bond. These unique properties make Maleimidocaproic acid hydrazide-HCl an invaluable tool in research across biological and chemical sciences.

175290-73-0

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175290-73-0 Usage

Uses

Used in Biochemistry and Molecular Biology:
MaleiMidocaproic acid hydrazide-HCl is used as a bioconjugation agent for creating covalent links between proteins and other molecules. Its hydrazide group allows it to conjugate with aldehydes and ketones in proteins, while its maleimide group reacts with thiol groups, forming stable thioether bonds. This dual functionality makes it an essential tool in the development of customized, functionally active bio-molecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, MaleiMidocaproic acid hydrazide-HCl is used as a component in drug delivery systems. Its ability to form stable bonds with proteins and other molecules enables the creation of targeted drug delivery systems, improving the efficacy and bioavailability of therapeutic agents.
Used in Diagnostic Applications:
In the field of diagnostics, MaleiMidocaproic acid hydrazide-HCl is used as a labeling agent for the detection and quantification of specific biomolecules. Its reactivity with thiol groups allows for the attachment of fluorescent or radioactive tags to proteins or other molecules, facilitating their detection in various assays and diagnostic tests.
Used in Research and Development:
In academic and industrial research settings, MaleiMidocaproic acid hydrazide-HCl is used as a key component in the synthesis and modification of bio-molecules. Its versatility in forming covalent bonds with a variety of functional groups makes it a valuable asset in the development of new drugs, diagnostic tools, and other biotechnological applications.

Check Digit Verification of cas no

The CAS Registry Mumber 175290-73-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,2,9 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 175290-73:
(8*1)+(7*7)+(6*5)+(5*2)+(4*9)+(3*0)+(2*7)+(1*3)=150
150 % 10 = 0
So 175290-73-0 is a valid CAS Registry Number.

175290-73-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanehydrazide hydrochlo ride (1:1)

1.2 Other means of identification

Product number -
Other names Maleimidocaproic acid hydrazide-HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:175290-73-0 SDS

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