175417-05-7

Basic information

• Product Name: (3S,4R)-3-[(R)-1-(t-butyldimethylsiloxy)ethyl]-4-[(R)-1-(2-hydroxybenzoyl)ethyl]-2-azetidinone
• Synonyms: (3S,4R)-3-[(R)-1-(t-butyldimethylsiloxy)ethyl]-4-[(R)-1-(2-hydroxybenzoyl)ethyl]-2-azetidinone
• CAS NO: 175417-05-7
• Molecular Weight: 377.556
• Mol File: 175417-05-7.mol

Chemical Properties

• CAS DataBase Reference: (3S,4R)-3-[(R)-1-(t-butyldimethylsiloxy)ethyl]-4-[(R)-1-(2-hydroxybenzoyl)ethyl]-2-azetidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-3-[(R)-1-(t-butyldimethylsiloxy)ethyl]-4-[(R)-1-(2-hydroxybenzoyl)ethyl]-2-azetidinone(175417-05-7)
• EPA Substance Registry System: (3S,4R)-3-[(R)-1-(t-butyldimethylsiloxy)ethyl]-4-[(R)-1-(2-hydroxybenzoyl)ethyl]-2-azetidinone(175417-05-7)

Safety Data

• Hazardous Substances Data: 175417-05-7(Hazardous Substances Data)

Upstream product

• 610-99-1 1-(2-Hydroxy-phenyl)-propan-1-on 
• 76899-07-5 (3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one 

Downstream Products

• 93711-85-4 (2R)-2-[(2S,3S)-3-{(1R)-1-(t-butyldimethylsilyloxy)ethyl}-4-oxoazetidin-2-yl]propionic acid 

Relevant articles and documents

A highly diastereoselective synthesis of a 1-β-methylcarbapenem intermediate using titanium enolate of 2′-hydroxypropiophenone

A key 1-β-methylcarbapenem intermediate is synthesized from a highly diastereoselective condensation between the titanium enolate of 2′-hydroxypropiophenone with 4-acetoxy-β-lactam followed by ozonolysis of the resulting ketone to the carboxylic acid.