175443-11-5

Basic information

• Product Name: ((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-propyl-amine
• Synonyms: ((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-propyl-amine
• CAS NO: 175443-11-5
• Molecular Weight: 372.348
• Mol File: 175443-11-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-propyl-amine(CAS DataBase Reference)
• NIST Chemistry Reference: ((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-propyl-amine(175443-11-5)
• EPA Substance Registry System: ((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-propyl-amine(175443-11-5)

Safety Data

• Hazardous Substances Data: 175443-11-5(Hazardous Substances Data)

Upstream product

• 123-38-6 propionaldehyde 
• 175443-13-7 ((R)-6-Bromo-1,2,3,4-tetrahydro-naphthalen-2-yl)-((S)-1-phenyl-ethyl)-amine 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 4133-35-1 6-bromo-2-tetralone 

Downstream Products

• 175443-14-8 {(R)-6-[((S)-1-Phenyl-ethyl)-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-yl}-methanol 
• 175443-16-0 [(R)-6-(4-Methoxy-benzenesulfonylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-((S)-1-phenyl-ethyl)-propyl-amine 
• 175443-15-9 [(R)-6-(4-Methoxy-phenylsulfanylmethyl)-1,2,3,4-tetrahydro-naphthalen-2-yl]-((S)-1-phenyl-ethyl)-propyl-amine 
• 175442-95-2 GR 218231 

Relevant articles and documents

Novel 6-substituted 2-aminotetralins with potent and selective affinity for the dopamine D3 receptor

Starting from (1S,2R)-5-methoxy-1-methyl-2-N,N-dipropylaminotetralin [(+)-UH-232] as a lead structure, a series of novel 6-substituted 2-aminotetralins have been discovered which show high affinity for dopamine D3 receptors. One compound, GR218231, exhibits ca. 400 fold selectivity for the dopamine D3 receptor over the D2 receptor and ca. 10,000 fold selectivity with respect to D1 and D4 receptors.