175473-06-0Relevant academic research and scientific papers
First synthesis of enantiomerically pure carbocyclic oxanosine as a potential chemotherapeutic agent
Kurata, Hiroko,Nishiyama, Shigeru,Yamamura, Shosuke,Kato, Kuniki,Fujiwara, Sari,Umezawa, Kazuo
, p. 283 - 286 (2007/10/03)
The first synthesis of optically active carbocyclic oxanosine 2 has been achieved in 14 steps from commercially available D-ribonic acid γ-lactone. When evaluated for the inhibition activity of NGF-induced differentiation on PC12 cells, 2 was about 10-fold less active than natural oxanosine. Copyright
