175476-73-0

Basic information

• Product Name: 3-(2-Hydroxy-3-methyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol
• Synonyms: 3-(2-Hydroxy-3-methyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol
• CAS NO: 175476-73-0
• Molecular Weight: 392.454
• Mol File: 175476-73-0.mol

Chemical Properties

• CAS DataBase Reference: 3-(2-Hydroxy-3-methyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Hydroxy-3-methyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol(175476-73-0)
• EPA Substance Registry System: 3-(2-Hydroxy-3-methyl-phenyl)-[1,1']binaphthalenyl-2,2'-diol(175476-73-0)

Safety Data

• Hazardous Substances Data: 175476-73-0(Hazardous Substances Data)

Upstream product

• 909187-39-9 2-methoxy-3-methylphenylboronic acid 
• 142010-72-8 3-Bromo-2,2'-bis-methoxymethoxy-[1,1']binaphthalenyl 

Downstream Products

• 175476-77-4 (C₂₆H₁₄O₃)H(CH₃)B(C₆H₃(CF₃)2) 

Relevant articles and documents

Design of bronsted acid-assisted chiral Lewis acid (BLA) catalysts for highly enantioselective Diels-Alder reactions

Bronsted acid-assisted chiral Lewis acid (BLA) was highly effective as a chiral catalyst for the enantioselective Diels-Alder reaction of both α- substituted and α-unsubstituted α,β-enals with various dienes. Hydroxy groups in optically active binaphthol derivatives and boron reagents with electron-withdrawing substituents were used as Bronsted acids and Lewis acids, respectively. Intramolecular Bronsted acids in a chiral BLA catalyst played an important role in accelerating the rate of Diels-Alder reactions and in producing a high level of enantioselectivity. In particular, excellent enantioselectivity was achieved due to intramolecular hydrogen bonding interaction and attractive π-π donor-acceptor interaction in the transition-state assembly by hydroxy aromatic groups in a chiral BLA catalyst.