175477-27-7Relevant academic research and scientific papers
Diastereoselective conversion of sulfides into sulfoxides. 1,5- and 1,6-asymmetric induction
Bower, Justin F.,Martin, Christopher J.,Rawson, David J.,Slawin, Alexandra M. Z.,Williams, Jonathan M. J.
, p. 333 - 342 (2007/10/03)
The diastereoselective oxidation of sulfides into sulfoxides has been achieved with enantiomerically pure dihydrooxazole auxiliaries. When an additional hydroxymethyl substituent is present, diastereocontrol is very high and 1,5-asymmetric induction has been achieved with up to 96:4 selectivity, and 1,6-asymmetric induction has been achieved with up to 97:3 selectivity in the absence of any additional chiral agents.
