175553-31-8

Basic information

• Product Name: 4-Piperidinecarboxylic acid, 1-[2-(4-fluorophenyl)ethyl]-, ethyl ester
• CAS NO: 175553-31-8
• Molecular Formula: C16H22FNO2
• Molecular Weight: 279.355
• Mol File: 175553-31-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-Piperidinecarboxylic acid, 1-[2-(4-fluorophenyl)ethyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarboxylic acid, 1-[2-(4-fluorophenyl)ethyl]-, ethyl ester(175553-31-8)
• EPA Substance Registry System: 4-Piperidinecarboxylic acid, 1-[2-(4-fluorophenyl)ethyl]-, ethyl ester(175553-31-8)

Safety Data

• Hazardous Substances Data: 175553-31-8(Hazardous Substances Data)

Upstream product

• 1126-09-6 4-carbethoxypiperidine 
• 332-42-3 (2-bromoethyl)-4-fluorobenzene 
• 40759-47-5 1-(2-methanesulfonyloxyethyl)-4-fluorobenzene 
• 243640-33-7 ethyl N-(4-fluorophenylthioacetyl)-4-carboxylpiperidine 
• 7589-27-7 2-(4-Fluorophenyl)ethanol 

Downstream Products

• 175553-32-9 1-[2-(4-fluorophenyl)ethyl]-4-piperidinecarboxylic acid N-methoxy N-methyl amide 
• 175673-57-1 (-)-MDL 100907 
• 139290-69-0 (2,3-dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol 
• 252364-39-9 4-[1-oxo-1-(2,3-dimethoxyphenyl)methyl]-N-2-(4-fluorophenylethyl)piperidine 
• 139290-65-6 R-(+)-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol 
• 881897-59-2 {1-[2-(4-fluorophenyl)-ethyl]-piperidin-4-yl}(phenyl)methanone 
• 252364-41-3 [2-methoxy-3-[(1,1-dimethylethyldiphenylsilyl)oxy]phenyl][1-[2-(4-fluorophenyl)ethyl]-4-piperidinyl]methanone 

Relevant articles and documents

Total synthesis and evaluation of [18F]MHMZ

Radiochemical labeling of MDL 105725 using the secondary labeling precursor 2-[18F]fluoroethyltosylate ([18F]FETos) was carried out in yields of ～90% synthesizing [18F]MHMZ in a specific activity of ～50 MBq/nmol with a sta

The "reverse-tethered" ruthenium (II) catalyst for asymmetric transfer hydrogenation: Further applications

The attachment of a tethering group from the basic nitrogen atom to the arene ligand of a ruthenium(II) catalyst greatly improves its ability to catalyze asymmetric transfer hydrogenation (ATH) reactions. In this paper, we describe further applications of this versatile system to an extended substrate range.

Novel processes for the preparation or (R)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol

The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme: