175601-94-2 Usage
Uses
Used in Pharmaceutical Synthesis:
2,3-dihydro-1H-Indole-3-acetamide is used as an intermediate in the synthesis of various pharmaceuticals and biologically active compounds due to its versatile chemical structure and properties.
Used in Organic Synthesis:
In the field of organic synthesis, 2,3-dihydro-1H-Indole-3-acetamide is utilized as a key building block for the creation of complex organic molecules, leveraging its unique molecular structure.
Used in Drug Development:
2,3-dihydro-1H-Indole-3-acetamide is used as a drug candidate for neurological disorders, capitalizing on its potential pharmacological properties and activity as a central nervous system stimulant.
Used in Research and Development:
In the scientific community, 2,3-dihydro-1H-Indole-3-acetamide is employed in research and development for exploring its pharmacological properties and potential applications in medicine and biology.
Used in the Chemical Industry:
2,3-dihydro-1H-Indole-3-acetaMide is also used in the chemical industry for the development of new chemical entities and materials, taking advantage of its reactivity and structural features.
Check Digit Verification of cas no
The CAS Registry Mumber 175601-94-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,5,6,0 and 1 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 175601-94:
(8*1)+(7*7)+(6*5)+(5*6)+(4*0)+(3*1)+(2*9)+(1*4)=142
142 % 10 = 2
So 175601-94-2 is a valid CAS Registry Number.
175601-94-2Relevant academic research and scientific papers
[11C]Enzastaurin, the first design and radiosynthesis of a new potential PET agent for imaging of protein kinase C
Wang, Min,Xu, Lu,Gao, Mingzhang,Miller, Kathy D.,Sledge, George W.,Zheng, Qi-Huang
experimental part, p. 1649 - 1653 (2011/05/11)
Enzastaurin (LY317615) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 value of ～6 nM. [11C] Enzastaurin (3-(1-[11C]methyl-1H-indol-3-yl)-4-[1-[1-(2- pyridinylmethyl)-4-piperidinyl]-1H-indol-3-yl]-1H-pyrrole-2,5-dione), a new potential PET agent for imaging of PKC, was first designed and synthesized in 20-25% decay corrected radiochemical yield and 370-555 GBq/μmol specific activity at end of bombardment (EOB). The synthetic strategy was to prepare a carbon-11-labeled maleic anhydride intermediate followed by the conversion to maleimide.
Strategies for the synthesis of N-(azacycloalkyl)bisindolylmaleimides: Selective inhibitors of PKCβ
Faul, Margaret M.,Grutsch, John L.,Kobierski, Michael E.,Kopach, Michael E.,Krumrich, Christine A.,Staszak, Michael A.,Udodong, Uko,Vicenzi, Jeffrey T.,Sullivan, Kevin A.
, p. 7215 - 7229 (2007/10/03)
N-(Azacycloalkyl)bisindolylmaleimides 1 have been identified to be selective inhibitors of PKCβ. This manuscript will describe the synthetic approaches employed to prepare this class of compounds that resulted in development of efficient methods for prepa
