175650-35-8

Basic information

• Product Name: <3,5-bis(trifluoromethyl)phenyl>diphenylphosphane
• Synonyms: <3,5-bis(trifluoromethyl)phenyl>diphenylphosphane
• CAS NO: 175650-35-8
• Molecular Weight: 398.287
• Mol File: 175650-35-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: <3,5-bis(trifluoromethyl)phenyl>diphenylphosphane(CAS DataBase Reference)
• NIST Chemistry Reference: <3,5-bis(trifluoromethyl)phenyl>diphenylphosphane(175650-35-8)
• EPA Substance Registry System: <3,5-bis(trifluoromethyl)phenyl>diphenylphosphane(175650-35-8)

Safety Data

• Hazardous Substances Data: 175650-35-8(Hazardous Substances Data)

Upstream product

• 299176-62-8 (3,5-bis(trifluoromethyl)phenyl)diphenylphosphine oxide 
• 1274868-04-0 3,5-bis(trifluoromethyl)phenylzinc bromide 
• 1079-66-9 chloro-diphenylphosphine 
• 402-31-3 1,3-bis(trifluoromethyl)benzene 
• 328-70-1 3,6-bis(trifluoromethyl)bromobenzene 

Relevant articles and documents

Anionic Palladium(0) and Palladium(II) Ate Complexes

Palladium ate complexes are frequently invoked as important intermediates in Heck and cross-coupling reactions, but so far have largely eluded characterization at the molecular level. Here, we use electrospray-ionization mass spectrometry, electrical cond

Chemoselective Reduction of Phosphine Oxides by 1,3-Diphenyl-Disiloxane

Reduction of phosphine oxides to the corresponding phosphines represents the most straightforward method to prepare these valuable reagents. However, existing methods to reduce phosphine oxides suffer from inadequate chemoselectivity due to the strength of the P=O bond and/or poor atom economy. Herein, we report the discovery of the most powerful chemoselective reductant for this transformation to date, 1,3-diphenyl-disiloxane (DPDS). Additive-free DPDS selectively reduces both secondary and tertiary phosphine oxides with retention of configuration even in the presence of aldehyde, nitro, ester, α,β-unsaturated carbonyls, azocarboxylates, and cyano functional groups. Arrhenius analysis indicates that the activation barrier for reduction by DPDS is significantly lower than any previously calculated silane reduction system. Inclusion of a catalytic Br?nsted acid further reduced the activation barrier and led to the first silane-mediated reduction of acyclic phosphine oxides at room temperature.

Strong π-acceptor sulfonated phosphines in biphasic rhodium-catalyzed hydroformylation of polar alkenes

A new series of sulfonated triarylphosphines with a strong π-acceptor character were synthesized by direct sulfonation of trifluoromethylated neutral phosphines. Due to the deactivating character of the trifluoromethyl group, high oleum concentration and the use of boric acid to prevent phosphine oxidation were required for the sulfonation step. The new sulfonated phosphines are water-soluble and more inert toward oxidation than classical sulfonated phosphines. The use of these trifluoromethylated and sulfonated phosphines as ligands in the biphasic hydroformylation of vinyl acetate and allyl cyanide increases the rate of the reaction up to 4 times, compared to the results obtained with the non-trifluoromethylated counterparts, TPPMS, TPPDS and TPPTS. Moreover, it is possible to recycle the catalyst without a significant loss of the system activity.