175666-91-8

Upstream product

• 98105-41-0 methyl S-3-cyclohexyl-2-(t-butoxycarbonylamino)propionate 
• 2043-61-0 cyclohexanecarbaldehyde 
• 251325-75-4 (2-cyclohexyl-1-formyl-vinyl)-carbamic acid tert-butyl ester 
• 121056-95-9 trimethyl 2-(tert-butoxycarbonylamino)phosphonoacetate 
• 251325-81-2 [2-cyclohexyl-1-(hydroxyimino-methyl)-vinyl]-carbamic acid tert-butyl ester 
• 98105-42-1 (S)-2-(t-butoxycarbonylamino)-3-cyclohexyl-1-propanal 
• 251325-59-4 (2-cyclohexyl-1-hydroxymethyl-vinyl)-carbamic acid tert-butyl ester 

Downstream Products

• 149423-46-1 (S)-tert-butyl (1-amino-3-cyclohexylpropan-2-yl)carbamate 
• 175666-96-3 {(S)-2-Cyclohexyl-1-[(R)-5-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-4,5-dihydro-isoxazol-3-yl]-ethyl}-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Asymmetric synthesis of β-amino alcohols and 1,2-diamines through DuPHOS-Rh catalysed hydrogenation

A novel enantioselective synthesis of β-amino alcohols and 1,2-diamines is reported which incorporates the first description of the asymmetric hydrogenation of dehydro-β-amino alcohols and dehydro-α-amino aldoximes.

Synthesis of 2-isoxazoline and α-hydroxy ketomethylene dipeptide isosteres

We have developed a simple and stereoselective method for synthesizing novel dipeptide isosteres using nitrile oxide cycloaddition as a key reaction. Employing this method, we have prepared efficiently various peptidomimetics containing 2-isoxazolines and