175692-57-6Relevant academic research and scientific papers
Design and Development of New Chemical Reactions via Low-valent Titanium-induced Cleavage of Carbon - Heteroatom Bonds
Talukdar, Sanjay,Banerji, Asoke
, p. 842 - 847 (2007/10/03)
Low-valent titanium (LVT)-induced regioselective cleavage of N-arylmethyl bonds in preference to N-alkyl/aryl counterparts in N-arylmethylamines has been examined in detail and culminated in the design and development of new reactions, viz. novel approach to deprotection of N-benzylamines, reductive deoxygenation of carbonyls to methylenes and reductive amination of carbonyls under neutral conditions - all involving a known bonding change, viz. the directed cleavage of C-N bonds via LVT-mediated reactions.
Low-valent titanium mediated reductive deoxygenation of carbonyls to methylenes via carbon-nitrogen bond cleavage in N-(arylmethyl) anilines
Talukdar,Banerji
, p. 1051 - 1056 (2007/10/03)
The reduction of aryl aldehydes and ketones in neutral medium, to the corresponding hydrocarbons via carbon-nitrogen bond cleavage of the intermediate N-(arylmethyl) anilines with low-valent titanium reagents is described. It provides a mild, convenient and selective pathway for deoxygenation of carbonyls without the production of any side product.
