17573-23-8

Basic information

• Product Name: 7,8-dihydrobenzo(a)pyrene
• Synonyms: 7,8-dihydrobenzo(a)pyrene
• CAS NO: 17573-23-8
• Molecular Formula: C₂₀H₁₄
• Molecular Weight: 254.34
• Mol File: 17573-23-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 128°C
• Boiling Point: 332.54°C (rough estimate)
• Flash Point: 218.9°C
• Appearance: /
• Density: 1.1180 (estimate)
• Vapor Pressure: 6.86E-08mmHg at 25°C
• Refractive Index: 1.7040 (estimate)
• CAS DataBase Reference: 7,8-dihydrobenzo(a)pyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 7,8-dihydrobenzo(a)pyrene(17573-23-8)
• EPA Substance Registry System: 7,8-dihydrobenzo(a)pyrene(17573-23-8)

Safety Data

• Hazardous Substances Data: 17573-23-8(Hazardous Substances Data)

Usage

General Description

7,8-dihydrobenzo(a)pyrene is a polycyclic aromatic hydrocarbon (PAH) that is formed during the incomplete combustion of organic matter, such as fossil fuels and wood. It is a known carcinogen and is classified as a group 1 human carcinogen by the International Agency for Research on Cancer (IARC). 7,8-dihydrobenzo(a)pyrene is commonly found in air pollution, tobacco smoke, and grilled or charred foods. It is metabolized in the body to form reactive intermediates that can bind to DNA and cause mutations, leading to the development of cancer. Exposure to 7,8-dihydrobenzo(a)pyrene has been linked to an increased risk of lung, skin, and bladder cancer, as well as cardiovascular and respiratory diseases. Therefore, efforts to reduce human exposure to this hazardous chemical are important for public health and safety.

InChI:InChI=1/C20H14/c1-2-7-17-15(4-1)12-16-9-8-13-5-3-6-14-10-11-18(17)20(16)19(13)14/h2-3,5-12H,1,4H2

Upstream product

• 17750-93-5 7,8,9,10-tetrahydrobenzo[a]pyrene 
• 17573-24-9 10-hydroxy-7,8,9,10-tetrahydrobenzopyrene 
• 84679-52-7 4-(pyren-2-yl)-butanoic acid 
• 57652-65-0 7,8,9,10-tetrahydrobenzopyren-10-one 
• 82799-71-1 2-pyrenylacetaldehyde 
• 82799-70-0 ethyl 2-pyrenylacetate 
• 82808-65-9 (4,5,9,10-tetrahydro-2-pyrenyl)acetic acid 
• 87337-31-3 ethyl 4-(2-pyrenyl)butanoate 
• 82799-69-7 ethyl 4,5,9,10-tetrahydro-2-pyrenylacetate 
• 87337-26-6 ethyl 3-bromo-4-(2-pyrenyl)butanoate 
• 87337-20-0 ethyl 3-hydroxy-4-(2-pyrenyl)butanoate 
• 3331-46-2 9,10-dihydrobenzo[a]pyren-(8H)-none 

Downstream Products

• 358967-88-1 trans-9-iodo-10-carbomethoxyamino-7,8,9,10-tetrahydrobenzo[a]pyrene 
• 79970-85-7 trans-9,10-bis(benzoyloxy)-9,10-dihydrobenzopyrene 
• 79970-84-6 C₃₄H₂₃BrO₄ 
• 58030-91-4 trans-9,10-dihydroxy-9,10-dihydrobenzopyrene 
• 358967-89-2 cyclic carbamate of cis-9-hydroxy-10-amino-7,8,9,10-tetrahydrobenzo[a]pyrene 
• 79970-83-5 trans-9,10-bis(benzoyloxy)-7,8,9,10-tetrahydrobenzopyrene 
• 61441-23-4 cis-9,10-bis(benzoyloxy)-7,8,9,10-tetrahydrobenzopyrene 

Relevant articles and documents

Acid catalysed reaction of indanones, tetralones and benzosuberone with neopentyl glycol and other alkanediols under forced conditions

Upon reaction with an excess of 2,2-dimethylpropane-1,3-diol (neopentyl glycol, NPG) under acid catalysis, indanones and tetralones yield indenes and dihydronaphthalenes, respectively. The reaction can also be carried out with butane-1,3-diol.

Improved Syntheses of (+/-)-trans-9,10-Dihydroxy-9,10-dihydrobenzopyrene and of (+/-)-trans-1,2-Dihydroxy-1,2-dihydrodibenzanthracene

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